Immigration in the National Interest Act of 2017 This bill amends the Immigration and Nationality Act to: eliminate the diversity visa program; replace the current employment visa system with a skills-based point system; revise the worldwide level of family-sponsored immigrants, including by eliminating certain family-based immigration preferences; establish a 50,000 annual limit for refugees given permanent resident status; create a nonimmigrant visa for parents of U.S. citizen children who are at least 21 years old; and establish a new visa for immigrants seeking to enter the United States to engage in a new commercial enterprise. The bill prohibits an alien from being be naturalized if his or her sponsor has not repaid the federal government for any means-tested public benefits received by the alien during the five-year period beginning on the date the alien was lawfully admitted for permanent residence.