Community Action Opioid Response Act of 2018 This bill requires the Office of Community Services within the Department of Health and Human Services to establish a grant program that helps low-income individuals, families, and communities affected by the national opioid epidemic. Grants must be awarded to Community Action Agencies (local organizations that work to reduce poverty in low-income communities) for specified activities relating to opioid misuse and abuse, including education, outreach, prevention, and treatment services.