Securing American Leadership in Science and Technology Act of 2020 This bill extends through FY2029 the Office of Science and Technology Policy (OSTP), the Office of Science of the Department of Energy, the Advanced Research Projects Agency-Energy, the National Institute of Standards and Technology (NIST), the National Oceanic and Atmospheric Administration, and the National Science Foundation (NSF). The bill sets forth programs, projects, and activities, including those regarding federal research security, the science and technical workforce, basic energy sciences research and upgrades to certain facilities, computational materials and chemistry science, advanced scientific computing, high energy physics, biological systems science and environmental science, fusion energy sciences research, nuclear physics, carbon utilization research infrastructure, enhanced geothermal energy, quantum information science and technology research, cybersecurity research, artificial intelligence and data science, engineering biology research, next generation digital radar, Antarctic nongovernmental activities and environmental liability requirements, and federal government inventions. The OSTP shall submit a comprehensive national science and technology strategy, and complete a review of U.S. science and technology enterprise. The Office of Science shall continue to leverage U.S. participation in the Large Hadron Collider, prioritize international partnerships and investments in the Long-Baseline Neutrino Facility/Deep Underground Neutrino Experiment, and prioritize international collaboration that would provide U.S. researchers access to the most advanced accelerator facilities in the world. The Government Accountability Office shall evaluate NIST's Center for Neutron Research. The NSF shall contract the National Academy of Public Administration to study the organizational and management structure of the NSF.