Regional Innovation Act of 2021 This bill establishes a Regional Technology and Innovation Hub Program and a Regional Clean Energy Innovation Program. The bill directs the Department of Commerce to establish the Regional Technology and Innovation Hub Program to encourage collaboration among local, state, and federal government entities, institutions of higher education, the private sector, nonprofit organizations, and others to promote inclusive regional innovation initiatives; designate eligible consortia as hubs and facilitate activities by such consortia in implementing their regional innovation strategies; and develop best practices for regional development and competitiveness in technology and innovation. Additionally, the Department of Energy shall establish the Regional Clean Energy Innovation Program to enhance the economic, environmental, and energy security of the United States; accelerate the pace of innovation of clean energy technologies through regional clean energy innovation partnerships; improve the competitiveness of U.S. clean energy technology research, development, demonstration, and commercial application; and support the development of tools and technologies best suited for use in diverse regions of the United States, including in rural, tribal, and low-income communities. Commerce shall carry out a program of data collection and analysis of technology and innovation sectors critical to realizing national objectives, including national security, economic prosperity, and social welfare.