The UPLIFT Act aims to combat the infiltration of transnational criminal organizations and rising crime by requiring law enforcement and public servants in sanctuary jurisdictions to fully cooperate with federal immigration agencies. Its stated purpose is to protect American citizens and mitigate the flow of illicit drugs by strengthening immigration enforcement. The bill significantly amends the Illegal Immigration Reform and Immigrant Responsibility Act of 1996, expanding the prohibition on state and local noncompliance with immigration laws . It prevents any government entity or individual from restricting officials from complying with or assisting in federal immigration enforcement. Specifically, it prohibits restrictions on law enforcement activities such as inquiring about immigration status of crime suspects, notifying the federal government about suspected inadmissible or deportable individuals, and complying with federal information requests. Furthermore, the legislation prohibits restrictions on government involvement with private immigration detention facilities , including entering agreements, selling property for their establishment, paying related costs, or receiving payments for detention services. It also grants local government entities standing to seek injunctive relief against their state for violations that cause harm. The Secretary of Homeland Security is mandated to annually determine and report which states or local entities are not in compliance. The bill also clarifies the authority of ICE detainers , defining probable cause for their issuance based on factors like biometric matches, ongoing removal proceedings, or prior removal orders. It sets a timeframe for the transfer of custody to the Department of Homeland Security, typically within 48 to 96 hours. Crucially, it grants immunity to state and local entities, and their personnel, that comply with ICE detainers, treating them as acting under federal authority and making the United States the proper defendant in related civil actions, except in cases of mistreatment. Finally, the Act establishes a private right of action allowing victims of murder, rape, or other felonies (or their families) to sue a state or local jurisdiction if the crime was committed by an alien released from custody due to the jurisdiction's failure to honor an ICE detainer. This provision aims to hold non-compliant jurisdictions accountable for the consequences of their actions.