This bill mandates collaboration between the Department of Homeland Security's Science and Technology Directorate and the Drug Enforcement Agency . The primary objective of this partnership is to significantly enhance the capacity to detect, identify, and disrupt illicit substances, specifically including nitazenes , even when present in very low concentrations. Furthermore, the legislation amends Section 302(15) of the Homeland Security Act of 2002. This amendment explicitly adds "nitazenes" to the list of substances, alongside fentanyl and xylazine, that the Department is directed to address, thereby broadening the scope of its drug detection efforts.